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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LONP1 All Species: 22.12
Human Site: Y725 Identified Species: 32.44
UniProt: P36776 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P36776 NP_004784.2 959 106489 Y725 K V L R K S A Y K I V S G E A
Chimpanzee Pan troglodytes XP_001143873 959 106437 Y725 K V L R K S A Y K I V S G E A
Rhesus Macaque Macaca mulatta XP_001088663 909 101136 T689 R C G R E R H T R R L S M R G
Dog Lupus familis XP_854391 960 106631 Y726 K V L R K S A Y K I V S G E A
Cat Felis silvestris
Mouse Mus musculus Q8CGK3 949 105824 Y714 K V L R K A A Y K I V S G E A
Rat Rattus norvegicus Q924S5 950 105774 Y715 K V L R K A A Y K I V S G E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506549 791 89382 G571 K Q Y C R E S G V R N L Q K Q
Chicken Gallus gallus XP_001232112 790 89040 R570 R Y L V P Q A R V L C G L D E
Frog Xenopus laevis Q2TAF8 856 94553 I617 E G S K S A T I N D T A D F A
Zebra Danio Brachydanio rerio Q5PQY6 840 92202 D620 P E M P I V I D H V A L K D I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649133 1006 112875 F748 K V I R K V A F R V V K K E G
Honey Bee Apis mellifera XP_392970 995 112847 F743 K V H R K V A F K V V K K E A
Nematode Worm Caenorhab. elegans O44952 971 108188 E719 K A A L Q I A E Q Q N E D E E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P93648 964 105641 S665 Q L V R Q G V S N E P D H E S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P93655 940 103912 L666 K I Y R K I A L K L V R E G A
Baker's Yeast Sacchar. cerevisiae P36775 1133 127093 P847 K L S I E D S P T S S A D S K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 86.6 93.7 N.A. 87.4 88.6 N.A. 71.6 73.8 32.2 32.7 N.A. 59.4 58.9 51.5 N.A.
Protein Similarity: 100 99.6 89 96 N.A. 92 92.8 N.A. 77 78.5 50.8 52.3 N.A. 73.3 74.9 67.2 N.A.
P-Site Identity: 100 100 13.3 100 N.A. 93.3 93.3 N.A. 6.6 13.3 6.6 0 N.A. 46.6 60 20 N.A.
P-Site Similarity: 100 100 40 100 N.A. 100 100 N.A. 26.6 33.3 33.3 20 N.A. 73.3 73.3 33.3 N.A.
Percent
Protein Identity: N.A. 48.7 N.A. 48.1 39.1 N.A.
Protein Similarity: N.A. 65.8 N.A. 65.4 57.1 N.A.
P-Site Identity: N.A. 13.3 N.A. 46.6 6.6 N.A.
P-Site Similarity: N.A. 46.6 N.A. 60 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 7 0 0 19 63 0 0 0 7 13 0 0 50 % A
% Cys: 0 7 0 7 0 0 0 0 0 0 7 0 0 0 0 % C
% Asp: 0 0 0 0 0 7 0 7 0 7 0 7 19 13 0 % D
% Glu: 7 7 0 0 13 7 0 7 0 7 0 7 7 57 13 % E
% Phe: 0 0 0 0 0 0 0 13 0 0 0 0 0 7 0 % F
% Gly: 0 7 7 0 0 7 0 7 0 0 0 7 32 7 13 % G
% His: 0 0 7 0 0 0 7 0 7 0 0 0 7 0 0 % H
% Ile: 0 7 7 7 7 13 7 7 0 32 0 0 0 0 7 % I
% Lys: 69 0 0 7 50 0 0 0 44 0 0 13 19 7 7 % K
% Leu: 0 13 38 7 0 0 0 7 0 13 7 13 7 0 0 % L
% Met: 0 0 7 0 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 13 0 13 0 0 0 0 % N
% Pro: 7 0 0 7 7 0 0 7 0 0 7 0 0 0 0 % P
% Gln: 7 7 0 0 13 7 0 0 7 7 0 0 7 0 7 % Q
% Arg: 13 0 0 63 7 7 0 7 13 13 0 7 0 7 0 % R
% Ser: 0 0 13 0 7 19 13 7 0 7 7 38 0 7 7 % S
% Thr: 0 0 0 0 0 0 7 7 7 0 7 0 0 0 0 % T
% Val: 0 44 7 7 0 19 7 0 13 19 50 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 13 0 0 0 0 32 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _